{"id":2207,"date":"2024-04-23T15:26:04","date_gmt":"2024-04-23T11:56:04","guid":{"rendered":"https:\/\/kimiakalarazi.com\/en\/?page_id=2207"},"modified":"2024-04-24T13:12:20","modified_gmt":"2024-04-24T09:42:20","slug":"ketoconazole-2","status":"publish","type":"page","link":"https:\/\/kimiakalarazi.com\/en\/ketoconazole-2\/","title":{"rendered":"ketoconazole 2%"},"content":{"rendered":"

[vc_row][vc_column]

<\/div>
<\/div>

ketoconazole 2%<\/span><\/h1>\n<\/div><\/div><\/div>
<\/div>[\/vc_column][\/vc_row][vc_row][vc_column width=”1\/2″]
\"\"<\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/2″]
\"\"<\/div>

Active ingredients:<\/h3>
\n
\n
Ketoconazole 2%<\/span><\/div>\n<\/div>\n<\/div>\n<\/div><\/div><\/div>
<\/div>
\"\"<\/div>

Indication:<\/h3>
\n
Anti-fungal, anti-dandruff, anti-seborrhoeic dermatitis<\/span><\/div>\n<\/div>\n<\/div><\/div><\/div>
<\/div>
\"\"<\/div>

Product differentiation:<\/h3>
\n
\n
–<\/span><\/div>\n<\/div>\n
<\/div>\n<\/div>\n<\/div><\/div><\/div>
<\/div>
\"\"<\/div>

Dosage:<\/h3>
\n
\n
\n
\n
\n5-10 ml<\/span>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
<\/div>\n<\/div>\n<\/div><\/div><\/div>[\/vc_column][\/vc_row][vc_row][vc_column]
<\/div>
Product Description<\/span><\/a>
[vc_column_text css=””]Background<\/strong>
\nt is an imidazole and works by hindering the production of ergosterol required for the fungal cell membrane, thereby slowing growth. Ketoconazole was patented in 1977 by Belgian pharmaceutical company Janssen, and came into medical use in 1981.
\nDrug category<\/strong>
\nImidazole antifungal class of medications
\nPharmacology and mechanism of action of the drug<\/strong>
\nketoconazole interacts with 14-\u03b1-sterol demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol. This results in inhibition of ergosterol synthesis and increased fungal cellular permeability due to reduced amounts of ergosterol present in the fungal cell membrane. This metabolic inhibition also results in accumulation of 14\u03b1-methyl-3,6-diol, a toxic metabolite. The increase in membrane fluidity is also thought to produce impairment of membrane-bound enzyme systems as components become less closely packed.
\n<\/span>[\/vc_column_text]<\/div><\/div>Precautions and warnings<\/span><\/a>
[vc_column_text css=””]Before using ketoconazole, tell your doctor or pharmacist if you are allergic to it; or to other azole antifungals such as clotrimazole, econazole, or miconazole; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
\nBefore using this medication, tell your doctor or pharmacist your medical history.
\nThis medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
\nIt is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
\n <\/span>[\/vc_column_text]<\/div><\/div>Storage<\/span><\/a>
[vc_column_text css=””]Store this medicine at below 25 \u00b0 C, and away from light and moisture.
\nKeep this medicine out of the reach and sight of children.<\/span>[\/vc_column_text]<\/div><\/div>Dosage and Instructions for Use<\/span><\/a>
[vc_column_text css=””]<\/p>\n