kalexit ® 15
Active ingredients:
Powder for Suspension
Indication:
Product differentiation:
Convenient to carry
Higher patient compliance
Easier to use
Both oral and rectal form use
Dosage:
Rectal: 30 g to 50 g every six hours
Background
Sodium polystyrene sulfonate (SPS) is a potassium-binding resin that is commonly used to treat mild hyperkalemia.
Drug category
potassium-removing agents
Pharmacology and mechanism of action of the drug
Polystyrene sulfonate, which is not absorbed, binds excess potassium, carrying it out of the body. The indigestible potassium polystryene sulfonate complex is excreted with the faeces, preventing the absorption of potassium into the blood stream. Hence, the serum potassium level decreases.
The FDA warning states that SPS may cause ‘Intestinal Necrosis: Cases of intestinal necrosis which may be fatal. Other serious gastrointestinal adverse events (bleeding, ischemic colitis and perforation) have also been reported in association with SPS use.
Use in Pregnancy:
Category C
Store this medicine at below 25 ° C, and away from light and moisture.
Keep this medicine out of the reach and sight of children.
Oral: The average total daily adult dose of sodium polystyrene sulfonate is 15 g to 60 g, administered as a 15-g dose (four level teaspoons), one to four times daily. Rectal: The average adult dose is 30 g to 50 g every six hours
Sodium polystyrene sulfonate (SPS) is a potassium binder that remove excessive amounts of potassium and is indicated for the treatment of hyperkalemia.